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KMID : 1037020140030010011
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Medical Lasers; Engineering, Basic Research, and Clinical Application
2014 Volume.3 No. 1 p.11 ~ p.16
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Clinical Benefit of Combination Treatment with 1,550 nm Fractional Laser and a New Wavelength at 1,927 nm on Photorejuvenation in Asian Patients
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Lee You-Jin
Chung Jong-Yoon
Lee Jae-Hyung
Lee Jong-Hee
Lee Joo-Heung
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Abstract
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Background and Objectives: Fractional laser using a new wavelength of 1,927 nm is expected to work on superficial skin conditions, while a 1,550 nm fractional laser was proven to be effective in dermal remodeling. We administered the combination treatment using 1,550 nm with 1,927 nm in a single session to determine its clinical efficacy and safety in photorejuvenation.Materials and Methods: Patients who received combination treatment were analyzed. Two blinded assessors graded the degree of improvement using photographs based on a quartile scale (0-3). Erythema and melanin index were measured on the same spot before and after treatment. Patients’ satisfaction and adverse effects were also reported.Results: A total of 25 patients were evaluated. Patients were followed up for up to 12 months (4.04 ± 2.78 months). The overall clinical improvement was 2.12 (Pigment improvement: 1.92 ± 0.84, wrinkle and skin texture; 1.66 ± 0.54). Melanin index showed a substantial decrease after treatments. One patient experienced post inflammatory hyperpigmentation, which subsided with administration of a topical bleaching agent after six months.Conclusion: Combination treatment with 1,550/1,927 nm may provide clinical benefit in Asian photoaged skin which contains a lot of pigmentation burden as well as wrinkles and other aging phenomenon.
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KEYWORD
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Combination treatment, Photorejuvenation
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